Every year, Strategic Radiology (SR) hosts a Virtual First Year in Practice Happy Hour for residents and fellows held in the fall. An annual highlight, the virtual event features a panel of early-career radiologists from SR groups responding to questions submitted by the radiology resident and fellow community. Part I of the article focused on preparing for real-world radiology; Part II continues with insider tips on how to navigate the interview process, avoid rookie mistakes, achieve work-life balance, and assess practice culture.